A natural boost for better well-being
SAM-e – or S-Adenosylmethionine – is a naturally occurring and, at the same time, one of the most important substances in the human body acting as a methyl group donor. SAMe helps in the production and regulation of hormones and the maintenance of cell membranes. It is involved in over 100 reactions in the human body. A delayed-release capsule product for the highest bioavailability. 
FEATURES:
– has a positive effect on liver function
– improves mood and has an antidepressant effect
– neuromodulator
– supports falling asleep and depth of sleep
– increases glutathione pool
– supports methylation
SAMe is a methyl donor, meaning that it shares methyl groups with other molecules in the body. Methyl groups are needed to speed up or maintain reactions in the body necessary for homeostasis. SAMe acts in the body in many ways, from the formation to breakdown of proteins, hormones and more.
The compound is involved in one of the final steps in the production of serotonin and dopamine called methylation. S-adenosylmethionine has a positive effect on liver function and conditions glutathione production.
Effects on the nervous system:
Taking a SAM-e supplement can increase the turnover of serotonin in the brain. It may also increase dopamine activity and inhibit norepinephrine reuptake. As these neurotransmitters may play a role in depression, SAM-e may reduce symptoms of depression in some people.
Improves sleep quality:
SAMe has a beneficial effect on people suffering from insomnia. It plays an important role in the synthesis of melatonin, a hormone associated with sleep. Melatonin has been studied as a treatment for insomnia, delayed sleep phase syndrome and diurnal rhythm disorders.
Deficiencies of folic acid and vitamin B12, essential cofactors in SAMe synthesis, may be responsible for reduced SAMe levels, especially in patients suffering from depression and dementia.
Preventive effect on joint health:
May promote collagen formation and thus contribute to maintaining joint comfort and normal mobility. SAMe has been most commonly used in adults at doses of 400-1600 mg orally daily for up to 12 weeks.
