RU58841 – 30 ml inhibits hair loss
Proprietary serum with highest effectiveness against hair loss now available!
RU58841 is a product that has been known for a long time, however, there was a problem with its availability on the Polish market. We meet the expectations and introduced a one-of-a-kind preparation that guarantees effectiveness against baldness!
What is and how does the product RU58841 work?
RU58841 + GHK-CU + melatonin + caffeine – none of these ingredients is inert! In addition, the whole is not mixed with DMSO, which can cause many side effects. The composition of the product is 100% well thought out and tested on many people.
- The most effective
- hair
- loss inhibitor,
- Reconstruction and regeneration of damaged hair,
- Reverses the effects of androgenetic alopecia (for many a necessity when using doping agents),
- Composition backed by many studies,
- Effectiveness of the composition backed by practice,
- Topical anti-androgenic effect without side effects as in the case of finasteride .
Dosage of the product and answers to frequently asked questions:
How to use?
Use the standard 1 ml (full volume of the pipette) per dose 1 x daily. Guide the pipette outlet close to the scalp so that the product does not settle on the hair.
How often to use?
One dose every day, at least until the hair stops falling out in excess (then the frequency should be adjusted individually).
Do I have to use the product all the time?
Yes, if you tend to have androgenetic alopecia. Not necessarily every day if you have managed to inhibit hair loss, however, the frequency of repeated applications will always be an individual issue.
Can women use the product?
Yes, if they are struggling with androgenetic alopecia. However, it is recommended to address the problem in the bud, that is, by reversing the hormonal disorders associated with androgen dominance.
Does it also work on facial hair?
Yes, it accelerates beard growth and prevents graying. GHK-Cu, melatonin and caffeine will be responsible for this process. RU58841 will have no effect on the beard.
Is it necessary to prepare for the application of the product?
Wash your hair beforehand, preferably with a shampoo with ketoconazole, like Nizoral, as this cleanses the hair follicles of accumulated DHT. It’s best to leave the lather on your head for a few minutes so the shampoo can actively work. Then wait a few minutes for the scalp to dry a bit. Up to 30 minutes after shampooing, the product should be applied.
Suggested dose
1 ml (the full volume of 1 pipette), and in the case of people resistant to the action of the specific, increase to 1.5-2 ml.
Due to the alcohol content, protect from contact with the eyes. If the product gets into the eyes, rinse with cool water.
LITERATURE:
- Strongly competes with DHT,
- Increases the rate of cellular replication in matrix cells,
- Increases cellular proliferation of outer root sheath cells,
- Increases hair diameter and density,
- Increases the percentage of hair in the anagen phase,
- No effect on hormonal balance ,
- Affects through local binding to the androgen receptor of the hair follicle,
- Is more effective than finasteride,
- Inhibits completely the negative effect on hair follicles of all androgen-anabolic steroids, which are analogues of DHT (masteron, but also trenbolone, dianabol), which gives it an advantage in effectiveness over other anti-androgens – finasteride, dutasteride (these in turn react fatally with SAAs such as NPP or deca-duarabolin)
DOI: 10.1016/0960-0760(94)90250-x
https://pubmed.ncbi.nlm.nih.gov/8326148/
GHK-Cu
Copper peptide caused enlargement of follicles on the skin of the back of rats, covering hair follicles. The effect was similar to that of topically applied minoxidil.
doi: 10.1111/1523-1747.ep12363275.
In the present study, it was proposed that AHK-Cu (close affinity to GHK-Cu) stimulates the growth of human hair follicles. The stimulatory effect may occur due to stimulation of proliferation and exclusion of apoptosis of dermal papilla cells; the dermal papilla regulates the development and growth of hair follicles. If copper peptides result in more dermal papilla cells, as suggested in this study, it seems likely that they may also stimulate hair growth. The multiplication of dermal papilla cells is one of the proposed methods for hair cloning.
doi: 10.1007/BF02978833.
https://link.springer.com/article/10.1007/BF02978833
The effects of the prototype drug Tricomin, consisting of a copper peptide. The results of the study suggest that it was about as effective as 2% minoxidil.
It promotes tissue regeneration, has anti-inflammatory effects and regulates gene expression.
doi: 10.3390/ijms19071987
https://www.mdpi.com/1422-0067/19/7/1987
Melatonin
Topically applied melatonin can affect hair growth in humans.
Melatonin led to a significant increase in the rate of anagen hair in occipital hair in women with androgenetic alopecia compared to placebo (n=12; P=0.012). For frontal hair, melatonin caused a significant increase in the group with diffuse alopecia (n=28; P=0.046). Occipital hair samples of patients with diffuse alopecia and the number of frontal hairs of those with androgenetic alopecia also showed an increase in anagen hair, but the differences were not significant. Plasma melatonin levels increased during melatonin treatment, but did not exceed the physiological nocturnal peak.
doi: 10.1111/j.1365-2133.2004.05685.x.
https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-2133.2004.05685.x
Topical application of cosmetic melatonin solution as a treatment option for androgenetic alopecia in both sexes (review of papers).
In 35 men with AGA, after 3 and 6 months, 54.8% to 58.1% of patients measured a significant increase in hair density of 29% and 41%, respectively (M0: 123/cm(2); M3: 159/cm(2); M6: 173/cm(2);) (P < 0,001). (4) In 60 men and women with hair loss, a significant reduction in female hair loss was observed, while male hair loss remained constant. In a large, 3-month, multicenter study involving more than 1,800 volunteers at 200 centers, the percentage of patients with 2- to 3-times positive hair loss decreased from 61.6% to 7.8%, while the percentage of patients with negative hair loss increased from 12.2% to 61.5% (p < 0.001). In addition, a reduction in seborrhea and seborrheic dermatitis was observed. Safety and tolerability were good in all studies.
doi: 10.4103/0974-7753.111199.
https://pubmed.ncbi.nlm.nih.gov/23766606/
Caffeine
Caffeine is a stimulator of human hair growth.
Significant growth inhibition was found in hair follicles treated with 5 µg/ml of testosterone, which in practice translates into an androgen-type alopecia mechanism. This was counteracted by caffeine at concentrations of 0.001% and 0.005%. Moreover, when the hair follicles were treated with caffeine alone – it led to a significant stimulation of hair follicle growth.
